SYNASE NASAL SPRAY CONSUMER INFORMATION:

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.

SYNASE (olopatadine hydrochloride) Nasal Spray, 665 micrograms (mcg) is a metered-spray solution for intranasal administration.

INDICATIONS

SYNASE Nasal Spray is an H1 receptor antagonist indicated for the relief of the symptoms of seasonal allergic rhinitis such as runny/itchy/stuffy nose, sneezing, and post-nasal drip in adults and children 6 years of age and older.

DOSAGE AND ADMINISTRATION

Administer SYNASE Nasal Spray by the intranasal route only.

Adults and Adolescents 12 years of age and older

The recommended dosage is two sprays per nostril twice daily.

Children 6 to 11 years of age

The recommended dosage is one spray per nostril twice daily.

HOW TO USE : Follow the instructions for properly priming the spray pump before using the bottle for the first time and if you have not used the medication for more than 7 days. Use this medication in your nose, usually twice a day in both nostrils or as directed by your doctor. Tell your doctor if your symptoms do not improve.

SIDE EFFECTS : A bitter taste in the mouth, nosebleeds, or irritation/soreness in the nose may occur. Drowsiness may rarely occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Most people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before using olopatadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history.

This drug may rarely make you drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use. Tell your doctor or pharmacist if you are taking other drugs that cause drowsiness such as: other antihistamines (such as cetirizine, diphenhydramine), anti-seizure drugs (such as carbamazepine), medicine for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:Store between 39-77 degrees F (4-25 degrees C). Protect from freezing. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed.